18 On the EJlctsqf Opium 



V I 



acted immediately oa the heart, could not iii 

 this instance be ej^pected to take place. 



(r) . Experiment 1 1 . , , • 



^, > A triangular piece of bone was takei>ffrom 

 jthe cranium ot a frog, and the dura and pia 

 mater removed; eight drops of the. strong so- 

 lution were injected upon the brain;, a, tew 

 drops wre lost. Intone; minute the a;>imal 

 Avas convulsed, in three minutes it w^s, djcai 

 On examination the irritability in every p/irt of 

 the voluntary muscles was destroyed, neither 

 compression, of the nerves nor mechanical irri- 

 tation could., excite aAy. contractions in them. 

 The heart had not lost its motion. 



(s) Experimeiit \2. 

 • In another experiment 6f the same kind, the 

 animal was immediately *and generally con- 

 vulsed, and was dead in one minute. When 

 the heart vvas exposed it was found contracting 

 42 times tli-a minute. The irritability of this 

 organ was not lost uiitil three hours after. 



. (t) Experiment 1%, 

 A portion of the cranium of a rabbit was 

 elevated in like manner, and 40 drops injected 



(r) Vid. Inaug, Dissert, p. 49» Exp. 29. 

 (s) Vid. p. 50. Exp. 31, 

 (t) Vid. p. 51. Exp. 33. 



