SM 



The Ohio Naturalist, 



[Vol. IX, No. 



the next generation. Inasmuch as healthy normal nuclei could 

 not be formed from parents which were degenerating, that evi- 

 dence applies to the parents as well as the descendants. In 

 exceptional cases, where they do not immediately fragment, 

 direct evidence of the fate of these nuclei due to amitosis by con- 

 striction can be secured. A few clusters of such nuclei have 

 been observed to persist unchanged until mitosis began. AVhen 

 this occurred they did not behave differently from the other 

 nuclei in any respect but formed spindles like them. In so far, 

 then, as the power to divide by mitosis is a test of the condition 

 of a nucleus, the products of this sort of amitosis must be regarded 

 as normal and similar in all respects to those, if there be any such, 

 which have descended bv an unbroken line of mitoses. 







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In the formation of these nuclei there is apparently no oppor- 

 tunity for the chromatin to be exactly equationally divided as in 

 mitosis. An inquiry into the number of chromosomes occurring 

 in mitoses following such divisions becomes therefore of primary 

 interest in view of the great importance now being accorded to 

 the number of chromosomes in our theories of heredity. In 

 studies along this line which the writer hopes to publish shortly 

 he expects to present evidence indicating, that in spite of the 



