486 NICOTIANA TABACUM. 
- Tobacco has been employed with some suc- 
cess in the locked jaw, both of warm and cold 
climates. Mr. Duncan, surgeon of Grenada, has 
published in the Edinburgh Journal the account 
of a very distressing case of this kind, which was 
relieved and finally cured principally by enemas 
of Tobacco smoke. These applications generally 
produced syncope and deathlike sickness in the 
patient, but by prudent management of them, the 
disease was entirely overcome, and recovery took 
place. Dr. Holmes of Worcester county, Mass. 
exhibited the infusion of Tobacco, to a patient 
under violent tetanus, after the more common 
remedies had been fully tried without effect. 
The spasms were completely remoyed and the 
patient recovered. 7 
This powerful medicine has been also em- 
ployed with some palliative effect in hydrophobia 
and certain other spasmodic diseases. Its in- 
ternal use however requires great caution, since 
patients have in various instances been destroyed 
by improper quantities administered by the 
hands of the unskilful or unwary. Notwithstand- 
ing the common use and extensive consumption 
of Tobacco in its various forms, it must unques- 
tionably be ranked among narcotic poisons of 
the most active class. The great prostration of 
