MUSHROOM POISONING 



venously tu supply the body's Deed for fluid and to ease th<- tortur 

 ing thirst. Narcotics and anodynes in large dose 

 to relieve the intense pain and t<> quiet convulsive movemei 

 Nitroglycerine and strychnia frequently, and ap t" the limit 



tolerance, are of great value. Cyi sis calls for oxygen inhal 



Atropine may !>•■ of use as a stimulant and .1 corrective with 1 

 phine bui it has no antidotal value here. .Milk, raw or boiled, 11 

 be regarded as a mil<l natural antidote Alcohol ^ 1 1 • • 1 1 1 < I probably 

 qoI be given in anj form. Strong coffee is indicated .1^ are 1 > • » t 

 dry applications to the body, Digitalis ma) !>«• u-t-.i bui requi 

 from six to ten hours b< fects are seen. Cam phot in sterile 



oil given subcutaneous^ every hour is valuable. Suprarenal 

 extract is mentioned. Large draughts of hot water, flaxseed I 

 slippery elm or starch water 14 may be used, as well as tannigen, 

 bismuth subcarbonate and opium t<» < 1 1 1 i < - 1 excessive diarrhea and 

 vomiting. Supportive measures and good nursing are of the - 

 est importance. Transfusion of blood would seem worthy of trial 

 in graver, slower cases. 



Ford, finding that protective and curative sera were theoretically 

 possible, worked for three years on the serum therapy. He was able 

 to immunize animals i<> the aqueous extrad up to five or Bis times 

 the fatal dose 18 i>ut efforts i<> manufacture ;i curative serum have 

 thus far been unsuccessful. 



The Pochier treatment by abscess of fixation has been applied by 

 Dr. A. Pic of the University of Lyon in -■'> ■ >f which 9 died. 



The conclusion that "it is a therapeutic agenl <>f the firsl order in 

 those terrible intoxications due t<» Amanita />h<ii 

 have made no impression on the medical profession. Judging from 

 Michigan cases 37 illnesses with 16 deaths this is nol a remark 

 ably low mortality, :'-'•' i«t <-<-h 1 versus 12. Pic and Martin conti 

 it with "the usual 86.8," based on -". v cases with 33 fatalities in 

 Prance, 1913. 



Poisonous Constituents imanita phaUo'u 



The firsl attempl to ••''tain the active principle or |x>if 

 l. phalloides is probably that «>! Letellier, who in 1821 

 hcai resistant substance from a number of fungi. This med 



amanitin. Later he found t«" substances, on< in in 



nature, acting upon the mucous membranes ot the aliment 

 canal and another characterized as ;• glucosidal alk;ili»i<l the 

 Amanitia. Boudier in 1866 ascribed the poisonous action t.» an 



