MUSHROOM POISONI2 



cotic of Inocybc infclix. (See below.) Atropin .1 antido 



The relationship of the toxins <>r /. infida and /. infclix \>> those of 

 A. mu8caria is ool yel clear. 



Tnocybe infclix, one of the mosl common Inocybes, closelj related 

 to tli<' preceding, has ool been tested for edibility, nor thus far 

 been reported ;i* toxic to man, inn its poison Beeins definite 11 nd 

 powerful. Ford and Sherriek 40 found it t<> contain ;i definite poison 

 which resists dessication and boiling. Small doses produced .1 •] 

 sleep in guinea pigs and rabbits from which they awoke well. \ 

 profound acute intoxication and coma, quickrj fatal, followed large 

 <losrv. The intoxication was such as is Been only uiili Lactat 

 tormino8us, ;i somnolence with retracted head (rabbits), passing 

 off in five hours. The action \\;is nut characteristically that of 1 

 muscaria, though no1 inconsistenl with muscarin, bul thai of a 

 narcotic of some sort. Further work is promised. Autopsy <>n 

 guinea pig showed hemorrhagic spots and perforating gastric ulcer. 

 Generally the examination was oegative. Tnocybe decipiens has 

 likewise do clinical record. Though its agglutinin is destroyed by 

 heat, the heated extract in - t<> i cc. doses aevertheless kill- guinea 

 pigs acutely — even in 20 minutes — due to dilated heart Smaller 

 doses bring on lachrymation, Balivation and nasal discharge, with 

 labored respirations. These symptoms last a few hours and disap 

 pear, but the animals die in a day. Occasionally hemmorhage into 

 the stomach is found postmortem. Dropped into the eye of rabbits, 

 the pupil contracts — resembling .1. muscaria ;iu<! muscarin. Boil 

 ing the extracl does no1 change its action. This Bigniflcanl record 

 entitles this [nocybe likewise to a place among the more dangerous 

 toadstools. 41 * ' 



Tnocybi sp. agrees in biologic pharmacology very closely with 

 the preceding and the same conclusions are justified in this new 

 addition to a bad family. Agglutinin powerful, bul thermolabile. 

 A muscarin-pilocarpine poison. 



Tin >,r\ 1 s 111 1:11 OM 1 



Eebeloma is closely related to [nocybe. The generic distinctions 

 may ho learned in order thai the mycophagist may rejecl both 

 genera as inedible. They never will be missed, anyway. Lil 

 is known aboul them. Eebeloma sinopizans is suspected (eaten 

 with a gay mixture which included 1'Amanita jaun< 

 Eebeloma instil, n> i-. related t" fnoci Koberl would class I. 



