152 PROCEEDINGS OF THE AMERICAN ACADEMY. 



litre. The elimination was apparently increased by the potassic iodide, 

 but the rate of elimination was not sufficiently studied. 



Miiller,* of Augsburg, in 1860, considers Kletzinsky's results to 

 have been not well established, and gives the following cases, which 

 are also detailed by Fabian, f who performed the analytical work. 



1. Man, aged 37. Symptoms: headache, loss of appetite, excess of 

 saliva, eructation, oppression after eating and vomiting, tongue slightly 

 coated, constipation. Medicine gave no relief, but absence from home 

 improved his general health. On return symptoms increased, and, in 

 addition, patient complained of pressure on brain and dizziness. The 

 wall paper had been sold as free from arsenic, but contained a large 

 quantity, and the color could be easily rubbed off. Fabian predicted a 

 negative result when asked to analyze the urine. December 13, 

 1859, after finding his reagents free from arsenic, he established the 

 presence of arsenic in 912 grams of urine. He went over his reagents 

 again with the same result, and an examination of a fresh quantity 

 of urine showed arsenic again. The urine was treated with potassic 

 chlorate and hydrochloric acid, evaporated, precipitated by sul- 

 phuretted hydrogen, and the precipitate thus obtained tested in the 

 Marsh apparatus. The wall paper was removed, and potassic iodide 

 prescribed (dose not stated). December 23, 812 grams of urine were 

 analyzed, and a greater quantity of arsenic was found than before, the 

 amounts in both cases being comparatively small. January 19, 1860, 

 912 grams of urine were found to be completely free from arsenic. 

 This in 37 days after taking the potassic iodide. Recovery followed 

 the removal of the paper. 



2-3. A woman, aged 27, and her child, 18 months, had lived for 

 some time in a room which was covered by a green unglazed paper, 

 in which arsenic and copper were found. The mother complained of 

 recurrent headache and pressure in the head. Both were extremely pale 

 and suffered from indigestion. January 28, 720 grams of the mother's 

 urine showed a trace of arsenic, after which the wall paper was removed 

 and potassic iodide prescribed. February 10, 692 grams showed an 

 increased amount. February 27, 716 grams showed a less amount, 

 and on March 27, 62 days after taking the iodide, the complete absence 

 of arsenic was proved. 



550 grams of the child's urine, examined January 28, yielded 

 no arsenic. This may perhaps find explanation in the fact that, 



* Wiener Wochenschrift, 1860, Heften 18, 19, 20, 21. 

 t Dingier, Polyt. Journ., CLVII. 212. 



