SANGER. — CHRONIC ARSENICAL POISONING. 161 



and there was marked improvement ; but on going back to the house 

 for August the symptoms appeared again, while return to the sea-shore 

 for September brought immediate relief. In the early autumn the 

 symptoms returned, but were not at their height until the furnace was 

 used. This was again thoroughly overhauled and the air of the bouse 

 tested for carbon monoxide with negative results. Mr. A.'s symp- 

 toms increased to a greater extent than those of the others, and were 

 accompanied by soreness of the abdomen and abdominal pains at 

 night. 



During the last week of December, 1885, the source of the trouble 

 was discovered by a qualitative analysis of the papers. Pending the 

 removal of the papers, the family left the house and experienced 

 immediate relief, especially in sleeping, but many of the symptoms 

 continued for some time afterward. January 7, 1886, a week after 

 leaving the house, 1,750 c.c. of Mr. A.'s urine were analyzed by the 

 method detailed above, and contained 0.01 mgr. arsenious oxide per 

 litre. The papers were replaced by absolutely non-arsenical paper 

 and the health of the family gradually came to its normal condition, 

 although there was occasional digestive disturbance. The elimination 

 of arsenic from the system was apparently very slow. 800 c.c. of 

 urine, analyzed March 31 (84 days), contained about as much as be- 

 fore, and 820 c.c, analyzed May 26 (140 days), contained 0.007 mgr. 

 per litre. Some time after this another sample of urine was sent to me 

 at Annapolis, and was set aside with several others until I should find 

 time to take up the subject again. So much time elapsed, however, 

 before the analyses could be made, that I do not consider the results 

 worthy of record. 



Case 2. Mr. C, aged 25, had for some years slept in a large room, 

 the paper of which contained from 10 to 15 mgr. arsenious oxide per 

 sq. m. (0.13 to 0.20 gr. per sq. yd.). The temperature was low, and 

 there was a good circulation of air in the room. At all events, no ill 

 effects were felt, and the urine, examined during January, 1886, con- 

 tained no arsenic. July 7, 1886, Mr. C. went to a house at the sea- 

 shore and occupied a small room, of which the paper contained 

 146 mgr. per sq. m. (1.88 gr. per sq. yd.). The area of paper was 

 about 22 sq. m. (26.3 sq. yd.). In addition the windows were hung 

 with red curtains about 4 sq. m. (4.8 sq. yd.) in surface, containing 

 151 mgr. per sq. m. (1.95 gr. per sq. yd.). Soon after taking the 

 room he began to suffer from indigestion with occasional bowel pains. 

 A qualitative analysis of the paper showing arsenic, the urine was 

 examined on July 15, and contained 0.042 mgr. per litre. Mr. C. 

 vol. xxix. (n. s. xxi.) 11 



