FORMATION OF GASTRULA. 



213 



four exoderm-cells makes its way into the middle of the 

 cell-mass, and, together with its three fellows, forms a pyra- 

 mid (or tetrahedron). The four exoderm-cells arrange 

 themselves in the form of a cap over the poin£ of this 

 pyramid (Plate II. Fig. 15). This is the beginning of a 

 germinal process which must be regarded as a shortened 

 and vitiated repetition of the inversion of the germ-mem- 

 brane vesicle, and which results in the formation of a Gas- 

 trula. From this time the further cleavage of the mam- 

 malian egg adheres to a rhythm which is most essentially 

 similar to that of the Frog's egff. While in the original 



© c>c> o 



(or primordial; egg- cleavage, the rhythm advances in regular 

 geometrical progression (2, 4, 8, 16, 32, 64?, 128, and so on) ; 

 in the modified progression of the mammalian egg, the 

 sequence of numbers is the same as that of the amphibian 

 egg : 2, 4, 8, 12, 16, 24, 32, 48, 64, 96, 160, etc' (Cf. Table V.) 



Fig. 41. — Gastrula of a 

 Mammal (Amphi gastrula of a 

 Rabbit), in longitudinal section 

 through the axis : e, exoderm- 

 cells (64 brighter and smaller) ; 

 i, entoderm-cells (32 darker and 

 larger) ; d, central entoderm- 

 cells, filling up the primitive in- 

 testinal cavity ; o, external ento- 

 derm-cells, plugging the primi- 

 tive mouth-opening (yelk-plug 

 in the " anus of Rusconi "). 



This depends on the fact that from this time the more 

 vigorous exoderm-cells increase at a quicker rate than the 

 more inert entoderm-cells. The latter always remain 

 behind the former, and are overgrown by them. This pro- 



