TABLE C4. HISTORICAL INCIDENCE OF ADRENAL MEDULLARY PHEOCHROMOCYTOMAS IN MALE 



B6C3Fi MICE RECEIVING NO TREATMENT (a) 



Study Incidence in Controls 



Historical Incidence at Southern Research Institute 



HC Blue No. 2 0/50 



C.I. Disperse Blue 1 1/49 



D-Mannitol 0/49 



Ziram 0/49 



Eugenol 0/43 



Propyl gallate 1/49 



Zearalenone 0/50 



HC Blue No. 1 2/49 



Stannous chloride 0/49 



TOTAL 4/437(0.9%) 



SD(b) 1.48% 



Range (c) 



High 2/49 



Low 0/50 



Overall Historical Incidence 



TOTAL (d) 25/1,962 (1.3%) 



SD(b) 1.78% 



Range (c) 



High 3/49 



Low 0/50 



(a) Data as of August 7, 1986, for studies of at least 104 weeks 



(b) Standard deviation 



(c) Range and SD are presented for groups of 35 or more animals. 



(d) Includes one malignant pheochromocytoma 



157 Nitrofurantoin, NTP TR 341 



