II. MATERIALS AND METHODS 



PROCUREMENT AND CHARACTERIZATION OF 



NITROFURANTOIN 

 PREPARATION AND CHARACTERIZATION OF 



FORMULATED DIETS 

 FOURTEEN-DAY STUDIES 

 THIRTEEN-WEEK STUDIES 



TWO-YEAR STUDIES 

 Study Design 



Source and Specifications of Animals 

 Animal Maintenance 

 Clinical Examinations and Pathology 

 Statistical Methods 



23 Nitrofurantoin, NTPTR 341 



