50 



45.0 



2 



< 40.0 



o 



>- 35.0 

 O 



UJ 



>_ 30.0 



Q 



O 



m 



z 



< 25.0 



20 0- 



15.0 



A 



IaA 



 • n 

 o 



. O Q ^ 

 O A 4i 



A 

 A 



9 A 



!• O'^O  .♦■■ -J 



OoaAaAa °.o 



A A A 4i A A A 



— 1 — 



30 45 60 



WEEKS ON STUDY 



— r — 

 75 



— I — 

 90 



50 



45.0 



40 



35.0 



30 



25.0 



- 20.0 



15 



105 



< 



o 



z 



I 

 o 



>- 

 Q 



o 

 m 



z 

 < 



50 



45 



40.0 



35.0 



30 



25 0- 



20.0 



15.0 



- 45 



9 S 



got 



 



A A A 



c 



A A 



: A 



— I — 

 90 



50.0 



40 



35 



30 



- 25.0 



20.0 



15.0 



105 



WEEKS ON STUDY 



FIGURE 11. GROWTH CURVES FOR MICE FED DIETS CONTAINING 

 NITROFURANTOIN FOR TWO YEARS 



53 



Nitrofurantoin, NTP TR 341 



