TABLE Dl. 



SUMMARY OF THE INCIDENCE OF NEOPLASMS IN FEMALE MICE IN THE TWO-YEAR 

 FEED STUDY OF NITROFURANTOIN (Continued) 



Untreated Control 



Low Dose 



High Dose 



TUMOR SUMMARY 



Total animals with primary neoplasms ** 30 



Total primary neoplasms 42 



Total animals with benign neoplasms 15 



Total benign neoplasms 17 



Total animals with malignant neoplasms 21 



Total malignant neoplasms 25 



Total animals with secondary neoplasms *** I 



Total secondary neoplasms 2 

 Total animals with neoplasms- 

 uncertain benign or malignant 



Total uncertain neoplasms 



35 

 55 

 15 

 17 

 27 

 37 

 2 

 3 



1 



1 



41 

 67 

 22 

 27 

 31 

 38 

 3 

 8 



2 

 2 



* Number of animals receiving complete necropsy examination; all gross lesions including masses examined microscopically. 



*• Primary tumors: all tumors except secondary tumors 



*•* Secondary tumors: metastatic tumors or tumors invasive into an adjacent organ 



169 



Nitrofurantoin, NTP TR 34! 



