TABLE E3. INDUCTION OF SISTER CHROMATID EXCHANGES IN CHINESE HAMSTER OVARY CELLS 



BY NITROFURANTOIN (a) 



Compound 



-S9 (c) 



Trial I -Summary: Equivocal 

 Dimethyl sulfoxide 

 Nitrofurantoin 



Mitomycin C 



Trial 2-Summary: Positive 

 Dimethyl sulfoxide 

 Nitrofurantoin 



Mitomycin C 



10 

 25 

 33 

 50 



0.001 

 0.01 



-HS9 (e) 



Trial 1 Summary: Weakly positive 

 Dimethyl sulfoxide 

 Nitrofurantoin 



Cyclophosphamide 



Trial 2--Summary: Weakly positive 

 Dimethyl sulfoxide 

 Nitrofurantoin 



Cyclophosphamide 



50 



50 



50 



50 



50 







50 

 5 



50 



50 



1 ,023 



1,012 



1 ,000 

 1,006 

 1,020 



1,013 

 101 



1,018 



1 ,020 



493 



0.48 



9.9 



26.0 



455 



532 

 623 



774 



602 

 153 



483 



0.45 



9.1 



26.0 



0.47 



9.7 



26.0 



457 



0.45 



9.1 



26.0 



Nitrofurantoin, NTP TR 341 



196 



