TABLE C5. SUMMARY OF THE INCIDENCE OF NONNEOPLASTIC LESIONS IN MALE MICE IN THE 

 TWO-YEAR FEED STUDY OF NITROFURANTOIN (Continued) 



Untreated Control Low Dose High Dose 



URINARY SYSTEM (Continued) 

 Urethra 



Inflammation, suppurative, subacute 



Bulbourethral gland, dilatation 

 Urinary bladder (50) (49) (50) 



Calculus gross observation 



Calculus micro observation only 



Inflammation, chronic 1 (2%) 



Inflammation, suppurative, acute 



Transitional epithelium, hyperplasia 



161 Nitrofurantoin, NTP TR 341 



