APPENDIX D 



SUMMARY OF LESIONS IN FEMALE MICE IN 



THE TWO-YEAR FEED STUDY OF NITROFURANTOIN 



PAGE 



TABLE Dl SUMMARY OF THE INCIDENCE OF NEOPLASMS IN FEMALE MICE IN THE 



TWO-YEAR FEED STUDY OF NITROFURANTOIN 165 



TABLE D2 INDIVIDUAL ANIMAL TUMOR PATHOLOGY OF FEMALE MICE IN THE TWO-YEAR 



FEED STUDY OF NITROFURANTOIN 170 



TABLE D3 ANALYSIS OF PRIMARY TUMORS IN FEMALE MICE IN THE TWO-YEAR FEED 



STUDY OF NITROFURANTOIN 182 



TABLE D4a HISTORICAL INCIDENCE OF OVARIAN TUMORS IN FEMALE B6C3Fi MICE 



RECEIVING NO TREATMENT 185 



TABLE D4b HISTORICAL INCIDENCE OF HEMATOPOIETIC SYSTEM TUMORS IN FEMALE 



B6C3Fi MICE RECEIVING NO TREATMENT 186 



TABLE D4c HISTORICAL INCIDENCE OF UTERINE GLANDULAR TUMORS IN FEMALE B6C3Fi 



MICE RECEIVING NO TREATMENT 187 



TABLE D4d HISTORICAL INCIDENCE OF HEPATOCELLULAR TUMORS IN FEMALE B6C3Fi 



MICE RECEIVING NO TREATMENT 188 



TABLE D4e HISTORICAL INCIDENCE OF LIVER ITO CELL TUMORS IN FEMALE B6C3Fi MICE 



RECEIVING NO TREATMENT 188 



TABLE D5 SUMMARY OF THE INCIDENCE OF NONNEOPLASTIC LESIONS IN FEMALE MICE 



IN THE TWO YEAR FEED STUDY OF NITROFURANTOIN 189 



163 



Nitrofurantoin, NTP TR 341 



