TABLE A3. ANALYSIS OF PRIMARY TUMORS IN MALE RATS IN THE TWO-YEAR FEED STUDY 



OF NITROFURANTOIN (Continued) 



Control 



1,300 ppm 



2,500 ppm 



Subcutaneous Tissue: Fibroma 



Overall Rates (a) 

 Adjusted Rates (b) 

 Terminal Rates (c) 

 Day of First Observation 

 Life Table Tests (d) 

 Logistic Regression Tests ( d ) 

 Cochran-Armitage Trend Test (d) 

 Fisher Exact Test (d) 



Subcutaneous Tissue: Fibroma or Fibrosarcoma 



Overall Rates (a) 



Adjusted Rates (b) 



Terminal Rates (c) 



Day of First Observation 



Life Table Tests Id) 



Logistic Regression Tests Id) 



Cochran-Armitage Trend Test (d) 



Fisher Exact Test (d) 



Testis: Interstitial Cell Adenoma 



Overall Rates (a I 



Adjusted Rates (b I 



Terminal Rates (c) 



Day of First Observation 



Life Table Tests (d) 



Logistic Regression Tests (d) 



Cochran-Armitage Trend Test (d) 



Fisher Exact Test (d ) 



Thyroid Gland: C-Cell Adenoma 



Overall Rates (a) 



Adjusted Rates (bl 



Terminal Rates (c) 



Day of First Observation 



Life Table Tests (d) 



Logistic Regression Tests (d) 



Cochran-Armitage Trend Test (d) 



Fisher Exact Test (d) 



Thyroid Gland: C-Cell Carcinoma 



Overall Rates (a) 



Adjusted Rates (b) 



Terminal Rates (c) 



Day of First Observation 



Life Table Tests (d) 



Logistic Regression Tests (d) 



Cochran-Armitage Trend Test (d) 



Fisher Exact Test (d) 



Thyroid Gland: C-Cell Adenoma or Carcinoma 



Overall Rates (a) 



Adjusted Rates (b) 



Terminal Rates (c) 



Day of First Observation 



Life Table Tests (d) 



Logistic Regression Tests (d) 



Cochran-Armitage Trend Test (d) 



Fisher Exact Test (d) 



97 



Nitrofurantoin, NTP TR 341 



