TABLE A4d. HISTORICAL INCIDENCE OF TESTICULAR TUMORS IN MALE F344/N RATS RECEIVING 



NO TREATMENT (a) 



Study Incidence of Adenomas in Controls (b) 



Historical Incidence at Southern Research Institute 



HC Blue No. 2 45/50 



C.I. Disperse Blue 1 44/49 



Eugenol 38/40 



Stannous chloride 34/50 



D-Mannitol 45/50 



Ziram 41/50 



Propyl gallate 47/50 



Zearalenone 45/50 



HC Blue No. 1 45/50 



TOTAL 384/439 (87.5%) 



SD(c) 8.21% 



Range (d) 



High 38/40 



Low 34/50 



Overall Historical Incidence 



TOTAL (6)1,681/1,909(88.1%) 



SD(c) 7.32% 



Range (d) 



High 49/50 



Low 34/50 



(a) Data as of August 7, 1986, for studies of at least 104 weeks 



(b) Diagnosed as interstitial cell tumors 



(c) Standard deviation 



(d) Range and SD are presented for groups of 35 or more animals. 



(e) Includes one malignant mterstitial cell tumor 



Nitrofurantoin, NTP TR 341 102 



