APPENDIX B 



SUMMARY OF LESIONS IN FEMALE RATS IN 



THE TWO-YEAR FEED STUDY OF NITROFURANTOIN 



PAGE 



TABLE Bl 



SUMMARY OF THE INCIDENCE OF NEOPLASMS IN FEMALE RATS IN THE 

 TWO-YEAR FEED STUDY OF NITROFURANTOIN 



111 



TABLE 82 



INDIVIDUAL ANIMAL TUMOR PATHOLOGY OF FEMALE RATS IN THE TWO-YEAR 

 FEED STUDY OF NITROFURANTOIN 



114 



TABLE B3 



ANALYSIS OF PRIMARY TUMORS IN FEMALE RATS IN THE TWO-YEAR FEED 

 STUDY OF NITROFURANTOIN 



126 



TABLE B4a 



HISTORICAL INCIDENCE OF CLITORAL GLAND TUMORS IN FEMALE F344/N 

 RATS RECEIVING NO TREATMENT 



129 



TABLE B4b 



HISTORICAL INCIDENCE OF MAMMARY GLAND TUMORS IN FEMALE F344/N 

 RATS RECEIVING NO TREATMENT 



130 



TABLE B5 



SUMMARY OF THE INCIDENCE OF NONNEOPLASTIC LESIONS IN FEMALE RATS 

 IN THE TWO-YEAR FEED STUDY OF NITROFURANTOIN 



131 



109 



Nitrofurantoin, NTP TR 341 



