TABLE B3. 



ANALYSIS OF PRIMARY TUMORS IN FEMALE RATS IN THE TWO-YEAR FEED STUDY 



OF NITROFURANTOIN 



Control 



600 ppm 



1,300 ppm 



Adrenal Gland: Pheochromocytoma 



Overall Rates (a) 

 Adjusted Rates (c) 

 Terminal Rates (d) 

 Day of First Observation 

 Life Table Tests (e) 

 Logistic Regression Tests (e) 

 Cochran-Armitage Trend Test (e) 

 Fisher Exact Test (e) 



Clitoral Gland: Adenoma 



Overall Rates (a) 

 Adjusted Rates (c) 

 Terminal Rates (d) 

 Day of First Observation 

 Life Table Tests (e) 

 Logistic Regression Tests (e) 

 Cochran-Armitage Trend Test (e) 

 Fisher Exact Test (e) 



Clitoral Gland: Carcinoma 



Overall Rates (a) 



Adjusted Rates (c) 



Terminal Rates (d) 



Day of First Observation 



Life Table Tests (e) 



Logistic Regression Tests (e) 



Cochran-Armitage Trend Test (e) 



FisherExactTest(e) 



Clitoral Gland: Adenoma or Carcinoma 



Overall Rates (a) 

 Adjusted Rates (c) 

 Terminal Rates (d) 

 Day of First Observation 

 Life Table Tests (e) 

 Logistic Regression Tests (e) 

 Cochran-Armitage Trend Test le) 

 Fisher Exact Test (e) 



Lung: Alveolar/Bronchiolar Adenoma or Carcinoma 



Overall Rates (a) 

 Adjusted Rates (c) 

 Terminal Rates (d) 

 Day of First Observation 

 Life Table Tests (e) 

 Logistic Regression Tests (e) 

 Cochran-Armitage Trend Test (e) 

 Fisher ExactTest(e) 



Mammary Gland: Fibroadenoma 



Overall Rates (a) 

 Adjusted Rates (c) 

 Terminal Rates (d) 

 Day of First Observation 

 Life Table Tests (e) 

 Logistic Regression Tests (e) 

 Cochran-Armitage Trend Test (e) 

 Fisher Exact Test(e) 



Nitrofurantoin, NTP TR 341 



126 



