TABLE B4a. HISTORICAL INCIDENCE OF CLITORAL GLAND TUMORS IN FEMALE F344/N RATS 



RECEIVING NO TREATMENT (a) 



Study 



Adenoma 



Incidence in Controls 



Carcinoma 



Adenoma or Carcinoma 



Historical Incidence at Southern Research Institute 



HC Blue No. 2 

 C.I. Disperse Blue 1 

 Eugenol 



Stannous chloride 

 D-Mannitol 

 Ziram 



Propyl gallate 

 Zearalenone 

 HC Blue No. 1 



TOTAL 



SD(b) 



Range (c) 

 High 

 Low 



Overall Historical Incidence 



TOTAL 

 SD(b) 



(d)39/l,984(2.0%) 

 2.31% 



(6)57/1,984(2.9%) 

 2.95% 



(d,e) 96/1 ,984 (4.8%) 

 3.40% 



Range (c) 

 High 

 Low 



5/49 

 0/50 



6/49 

 0/50 



6/49 

 0/50 



(a) Data as of August 7, 1986, for studies of at least 104 weeks 



(b ) Standard deviation 



(c) Range and SD are presented for groups of 35 or more animals. 



(d) Includes one cystadenoma, NOS 



(e) Includes five squamous cell carcinomas and five adenocarcinomas, NOS 



129 



Nitrofurantoin, NTP TR 341 



