TABLE C2. 



INDIVIDUAL ANIMAL TUMOR PATHOLOGY OF MALE MICE IN THE TWO-YEAR FEED 

 STUDY OF NITROFURANTOIN: LOW DOSE 



WEEKS ON 

 STUDY 



CARCASS 

 ID 



ALIMENTARY SYSTEM 

 Esopha^s 

 Gallbladder 

 Intestine large 

 Intestine large, cecum 

 Intestine large, colon 

 Intestine large, rectum 

 Intestine small 

 Intestine small, duodenum 

 Intestine small, ileum 

 Intestine small, jejunum 



Lymphoma mahgTiant lymphocytic 

 Liver 



Hemangiosarcoma 



Hepatocellular carcinoma 



Hepatocellular carcinoma, multiple 



Hepatocellular adenoma 



Hepatocellular adenoma, multiple 



Lymphoma malignant histiocytic 

 Mesentery 



Lymphoma malignant histiocytic 

 Pancreas 

 Salivary glands 

 Stomacn 



Stomach, forestomach 

 Stomach, glandular 

 Tooth 



CARDIOVASCULAR SYSTEM 



Heart 



ENDOCRINE SYSTEM 



Adrenal gland 

 Adrenal gland, cortex 



Adenoma 



Spindle cell, carnnoma 

 Adrenal gland, medulla 

 Islets, pancreatic 



Adenoma 

 Parathyroid giand 

 Pituitary gland 

 Thyroid gland 



GENERAL BODY SYSTEM 



None 



GENITAL SYSTEM 



Epididymis 

 Penis 



Preputial gland 

 Prostate 

 Seminal vesicle 

 Testes 



+ f 



M 

 M 



M 



Nitrofurantoin, NTP TR 341 



146 



