TABLE C2. INDIVIDUAL ANIMAL TUMOR PATHOLOGY OF MALE MICE: HIGH DOSE 



(Continued) 



WEEKS ON 

 STUDY 



CARCASS 

 ID 



HEMATOPOIETIC SYSTEM 

 Bone marrow 

 Lymph node 



Pancreatic, lymphoma malignant mixed 

 Lymph node, mandibular 



Bronchial, mediastinal, 

 alveolar/bronchiolar carcinoma, 

 metastatic, lung 

 Lymph node, mesenteric 



Lymphoma malignant histiocytic 



Lymphoma malignant mixed 

 Spleen 



Lymphoma malignant histiocytic 



Lymphoma malignant lymphocytic 



Lymphoma malignant mixed 

 Thymus 



Mediastinum, fibrosarcoma, metastatic, 

 skin 



INTEGUMENTARY SYSTEM 



Mammary gland 



Skin 

 Subcutaneous tissue, fibroma 

 Subcutaneous tissue, fibrosarcoma 

 Subcutaneous tissue, fibrosarcoma, 

 multiple 



MUSCULOSKELETAL SYSTEM 

 Bone 



Skeletal muscle 

 Diaphragm, intercostal. 

 alveolar/broncbiolar carcinoma, 

 metastatic, lung 



NERVOUS SYSTEM 



Brain 



RESPT!UTORY SYSTEM 



Lung 

 Alveolar/bronchiolar adenoma 

 Alveolar/bronchiolar carcinoma 

 Alveolar/bronchiolar carcinoma. 



multiple 

 Hepatocellular carnnoma. metastatic. 



liver 

 Lymphoma malignant histiocytic 



Nose 



Trachea 



SPECIAL SENSES SYSTEM 



Ear 



Hardenan gland 

 Adenoma 



URINARY SYSTEM 



Kidney 



Lymphoma malignant mixed 

 Unnary bladder 



1 I I L 1 

 

 5 5 5 



1 I I 

 

 5 5 5 



X 



•I- + 



M M M M M 



+ + + + ■*- + + 

 +• + + + + ■*- + 



M M M M 



+ + + + + + -h + + + + + + 

 XXX X 



X 



-t- -t- + + ■<■ 

 + >■■»- + ^- 



Nitrofurantoin, NTP TR 341 



152 



