TABLE D5. SUMMARY OF THE INCIDENCE OF NONNEOPLASTIC LESIONS IN FEMALE MICE IN THE 



TWO-YEAR FEED STUDY OF NITROFURANTOIN 



CARDIOVASCULAR SYSTEM 

 None 



ENDOCRINE SYSTEM 

 Adrenal gland, cortex 



Accessory adrenal cortical nodule 



Congestion 



Cyst 



Degeneration, fatty 



Spindle cell, hyperplasia 

 Adrenal gland, medulla 



Hyperplasia 

 Pituitary gland 



Pars distalis, angiectasis 



Pars distalis, hyperplasia 

 Thyroid gland 



Follicle, cyst 



Follicle, degeneration, cystic 



Follicle, hyperplasia, cystic 



(50) 



(50) 



1 (2%) 



189 



Nitrofurantoin, NTP TR 341 



