TABLE Fl. 



MURINE VIRUS ANTIBODY DETERMINATIONS FOR RATS AND MICE IN THE TWO-YEAR 

 FEED STUDIES OF NITROFURANTOIN (a) 



Interval (months) 



Number of 

 Animals 



Positive Serologic 

 Reaction for 



RATS 



2/10 

 10/10 



RCV 

 Sendai 



12 



1/10 

 9/10 



RCV 

 Sendai 



18 

 24 



4/9 



3/10 

 2/10 



Sendai 



Sendai 

 KRV 



MICE 



6 

 12 

 18 

 24 



10/10 



4/10 



9/9 



5/10 



Sendai 

 Sendai 

 Sendai 

 Sendai 



(a) Blood samples were taken from sentinel animals at 6, 12, and 18 months after the start of dosing and from the control 

 animals just before they were killed; samples were sent to Microbiological Associates (Bethesda, MDjfor the Animal Disease 

 Screening Program. 



203 



Nitrofurantoin, NTP TR 341 



