Appendix 1. (^conunuca; 



eosinophilic inflltrotlon In the well of some eWeoll end bronchi end 



sometimes In their lumen, with the neutrophils. Further from the moln 



inflammatory foci that contain the parasites, we often note alveolar 



edema and a mild infiltration of neutrophils and eosinophils. The muscles 



around the bronchioli are often hypertrophied, and we find a moderate 



amount of corpora amilacea (small calcified plagues) in the lumen of 



bronchi, bronchioli and alveoli, and sometimes incorporated into their 



wall, both of these lesions are not always seen in relation with the 



inflammatory foci. We also note ocasionnal giant cells in airways, with 



very few larvae, and a multifocal mild to moderate accumulation of 



Gram-negative bactehae sometimes associated with the lesions. 



-mediastinal and cervical lymph nodes: There Is a mild to moderate 



eosinophilic Infiltration In the mildly edematous cortex and In the 



medullary sinuses, where It Is accompanied by a few macrophages and 



some red blood cells. The cortex contains very few follicles. 



-heart: We note very few small foci of fibrosis In the myocardium, and a 



small to moderate amount of llpofuscln In the cardlomyocytes, around the 



nuclei. 



-aorta: No significant lesion. 



-diaphragm: No significant lesion. 



-thymus: Only some very thin thymus remnants are still there, and they 



ore poorly cellular. 



-liver In addition to a mild atrophy of the centrolobular hepatic cords, 



there Is a small amount of brown pigmet In the cytoplasm of the 



hepatocytes. 



-spleen: The white pulp It made of a large number of follicles that have a 



large germinal center with a very thin outer ring of mature lymphocytes. 



-pancreas: No significant lesion. 



-thyroid: Most of the follicles contain little colloid, but the autolysis is 



moderate. Some Intact follicles contain a normal amount of colloid. 



-adrenals: The cortex/medulla ratio Is low, and the junction Is Irregular. 



184 



