III. HUMAN GENETIC MUTANT CELL REPOSITORY 



MINIMUM SAFETY GUIDELINES 



RECOMMENDED FOR WORKING WITH LYMPHOID 



AND VIRUS TRANSFORMED HUMAN CELL LINES* 



A. Supervision 



1. Administrative Responsibilities 



a. Responsibility of Management 



Management should establish a biohazards committee to insti- 

 tute and enforce a health and safety policy which includes a 

 specific safety program for work involving human cell lines. 

 The program should meet applicable federal, state and local 

 regulations and include safety training, maintenance of accident 

 records, and provisions for emergency treatment. 



b. Responsibility of the Principal Investigator 



The principal investigator is responsible for the prepara- 

 tion of safety protocols for the research program under his 

 direction. The protocols should include appropriate procedures 

 for use, storage, decontamination, disposal and emergency treat- 

 ment. The protocols should be approved by the biohazards 



*These guidelines were developed on February 11, 1974 at a special 

 meeting at the National Institutes of Health attended by represent- 

 atives from the Office of Biohazards of NCI, NIAID, NIGMS and the 

 Advisory Committee to the Human Genetic Mutant Cell Repository. 



12 



