APPENDIX E 

 NSF CELL CULTURE CENTERS 



The Cell Culture Centers at the Massachusetts Institute 

 of Technology and the University of Alabama at Birmingham are 

 accepting applications for large scale cell and virus production 

 required for highly meritorious research projects. These centers 

 established by the National Science Foundation are intended to 

 serve as a facility and research resource for scientists through- 

 out the country. 



The MIT Center is headed by Dr. Phillips W. Robbins of MIT 

 and Dr. Richard L. Davidson of Harvard Medical School. This 

 facility is designed for large scale monolayer and suspension 

 cultures and has experience with a large number of different 

 cell lines and viruses and also with diploid human fibroblasts. 

 The University of Alabama center is headed by J. Claude Bennett 

 of the Department of Microbiology and Ronald T. Acton of the 

 Diabetes Research and Training Center. This facility is designed 

 for large scale suspension cultures with a capability of pro- 

 ducing one kilogram or more of cells per week. Their experience 

 to date is is primarily with lymphoblastoid cell lines. The 

 purpose of these centers is to produce cells and viruses on a 

 large scale in order to allow scientists to conduct novel and 

 important experiments in basic biological research that could 

 not be accomplished with the materials and resources in the 

 investigators' own laboratory. Approval of applications is on 



164 



