342 Transactions. 



Exp. 29. 

 P m_ Pigeon (adult). Weight, 368 grams. 



4.56. Gave 10-6 minims of a 5-per-cent. solution tutin (10 mlgm. per kilo), per os. 



5.14. Vomiting. 



5.21. Slight convulsive movements of wings. 



5.45. Restless. 



8.30. Apparently normal. 



Result. — Recovered from a dose of 10 mlgm. per kilo. 



Exp. 30. 

 P ji. Pigeon. Weight, 315 grams. 



2.50. Gave ir2 minims of a 0-5-per-cent. solution tutin (10-2o mlgm. per kilo), per os. 

 3.18. Tremulous; jerking of head ; restless; blinking. 



3.20. Tonic spasm of wings ; paroxysms of difficult breathing, during which bird turns 



round and round in one place. 

 3.40. Retching. 

 3.48. General convulsion, lasting 30 seconds, in which bird tumbles about in every 



direction. 



3.51. Lying on side, trembling and breathing very rapidly ; pupils normal. 



3.53. General convulsion ; pupils wide. 



3.54. General convulsion. 



3.56. Recovered upright position, and sat for a few seconds on its tail ; was then 

 seized with severe convulsions, which continued without intermission till 

 death. 



4.5. Died. 



Exps. 31, 32. (See text.) 



Exp. 33. 

 P_5i_ Lizard (Lygosoma moco). Weight, 4 gi-ams. 



5.15. Gave 3 '4 minims of a 0'01-per-cent. solution tutin (5 mlgm. per kilo), under the 



skin of the abdomen. 



6.15. Apparently normal. 



7-10. Quiet when first seen ; then took tits of abnormal activity, contorting itself, hold- 

 ing its fore limbs wide stretched, and resting on belly. 



7.55. Lying quiet, with mouth partially open. 



8.5. Seems quite dead ; mouth still more widely open. 



Exp. 34. 

 pji. Lizard. Weight, 5 grams. 



3.0. Gave 2-5 muiims of a 0'01-per-cent. solution (3 mlgm. per kilo), under the skin of 



the abdomen. The breathing became exaggerated almost immediately, and 



the animal puffed itself up as a frog does. 

 7.30. Nothing remarkable has been noticed. 

 Next day, 9 a.m. Apparently normal. 



Exp. 35. 



pyi Lizard. Weight, 7 gi'ams. 



4.35. Gave 5 minims of a 0'01-per-cent. solution of tutin (4 mlgm. per kilo), hypo- 



dermically. 

 7.20. Remarkable convulsive effects, opisthotonus and twisting into a ball with tail 



up to mouth, then clonic spasms of limbs ; after this was quiet for a time, and 



then movements began again ; lies on back biting at its own tail and hind 



limbs. 

 7.45. Has been quiescent for last five minutes ; now puffing itself up ; lying in normal 



position. 

 7.58. Another severe fit coming on suddenly ; animal twists rapidly into every possible 



attitude. 

 8.2. Still in constant movement, now more often on its back. 

 8.15. Quieter again. 

 8.25. Another period of restlessness. 

 8.35. Has quiet intervals. 

 8.55. Occasional movements. 

 9.15. Seems quite dead, but gave reflex response from limbs, and did not move after 



that. 



