336 Transactions. 



P.M. 



5.34. General convulsion. 



5.36. Up again ; takes no notice when called ; lying panting, with mouth open. 

 6.0. Has continued twitching every few minutes since last note ; now getting verj- 

 marked. 



6.5. Severe general convulsion, lasting 1 minute. 



6.6. Rose again ; pupils widely dilated when convulsed, diminish in size in the 



intervals. 

 7.15. The cat has not been seen since last note till now ; it is sitting on its haunches, 



tremulous, " miaus " when approached. 

 7.40. Same. 



8.30. Sitting quietly ; easily startled. 

 9.30. Apparently recovered ; no symptoms noticed. 

 Next day, 9 a.m. Seems quite well. 



Exp. 5. 



A.M. Rabbit. Weight, 0'729 kilograms. 



10.43. Gave 5 minims of a 0'5-per-cent. solution tutin (2 ralgm. per kilo), hypodermically. 

 11.15. No apparerrt change. 

 12.0. Standing in middle of cage ; does not appear at ease. 



P.M. 



12.10. Animal near front of cage ; semi-dazed ; starts when disturbed. 

 1.10. Much the same, quiet and dazed-looking. 

 2.10. Seems normal. 

 3.0. Gave some food. 



5.0. Food untouched, but no obvious symptoms. 

 Next day. Quite well. 



Exp. 6. 

 A_]VI, Rabbit. Weight, 962 grams. 



9.56. Gave 8'2 minims of a 0"5-per-cent. solution of tutin in normal saline (2"5 nilgm. 



per kilo). 

 11.0. Noticed to be in convulsions ; last seen about 10.30, was then quiescent. 



11.10. Sitting \ip ; dazed-looking. 



11.11. Another convulsion began, fell on side, clonic spasms; head bent back, ears 



twitching. 

 11.17. Still in convulsions. 

 11.32. Con^Tdsions. 



11.52. Lying on side, head bent back ; running-movements. 

 12.22. Died. 



Exp. 7. 

 A jj Rabbit. Weight, 788 grams. 



10.4. Gave 8 minims of a 0'5-per-cent. solution tutin (3 mlgm. per kilo). 



10.50. Slow, deliberate winking. 



10.55. Lying on right side ; breathing laboured. 



11.4. In clonic convulsions, with movements of jaw and exposure of teeth. 



11.15. Still in almost constant convulsion. 



11.20. Dead. 



Exp. 8. 

 p_jj_ Rabbit. Weight, 1-507 kilograms. 



5.12. Gave 38-4 minims of a 0-5-per-cent. solution tutin (7-5 mlgm. per kilo), per os. 



Was not watched constantly, but at — 

 5.45. Was found to show great rapidity of respirations ; alteration in gait — e.g., moved 



forward with difficulty, with body elongated, and abdomen trailing on floor ; 



then lay on abdomen, with hind legs projecting behind, twitching of eyes and 



ears. 

 6.5. Was found in severe general convulsions, head retracted, tonic spasms well 



marked ; running-movement of legs between fits ; was held up by the ears, 



but this did not influence the convulsions, and no influence when suspended 



by hind legs. 

 6.25. Constant movements, either convulsive seizures in which the head is always 



firmly retracted, or running-movements ; is quite unconscious ; eyes wide 



open, and, as it lies on its side, rubs the open lower eye into the sawdust during 



seizures. 

 6.45. Dead. 



