356 Transactions. 



P.M. 



12.32. Same ; lying on left side, with occasional kicking-movements. 



12.34. All movement ceased, except that heart can be seen beating by movement of 



hairs over precordial region. 

 12.36. Dead. 



P.M. — Stomach not distended ; contained only food ; blood-film taken from the 

 left ventricle only ; heart had ceased beating ; lungs not congested ; bladder full. 



Result. — 10 mlgm.. per kilo caused death in less than one hour. 



Exps. 140-151. 



Experiments 140 to 151 inclusive referred to the blood-pressure work, details ot 

 which are omitted. 



Exp. 152. 

 P.M. Cat. Weight, 3-52 kilograms. 



3.(). Chloroform administered with a Skinner's mask. The skin was reflected, the 



cranium trephined over the right parietal region, and the bone removed with 



bone forceps until the greater part of the right cerebral hemisphere was exposed. 



4.10. 50 minims of a 0-5-per-cent. solution tutin was injected hypodermically, and the 



administration of the anaesthetic discontinued. 

 4.24. As no symptoms had ajipeared, 25 minims of a 0-5-per-cent. solution tutin was 



injected into the peritoneum. 

 4.32. Slight twitching of the head and ears noticed, followed in a minute or two by con- 

 vulsive movements of the paws. The right cerebral hemisphere was imme- 

 diately scooped out. The con-\ailsive movements continued as before, affecting 

 both sides equally. The left cerebral hemisphere was then removed. The 

 convulsive movements continued. The breathing was greatly exaggerated, and 

 at intervals large quantities of urine were shot out with considerable force. 

 4.45. The spinal cord was then divided at the level of the 5th doi'sal vertebra. 

 4.49. Spasmodic movements of the hind limbs ; the limbs were rigidly flexed on the 



abdomen and shaken with clonic spasms. 

 4.54. Movements of fore paws. 



^.56. Slow spasmodic movements of hind limbs, the slow rigid movement towards 



the abdomen ending in clonic spasms. The reflexes in the hind limbs are 



exaggerated, the legs being quickly drawn up, and showing clonic movements. 



6.0. The fore limbs have been quiescent for some time ; movements occiuring in the 



hind limbs only. 

 5.3. Reflexes still markedly exaggerated (clonus) in the hind limbs, but cannot be 



elicited from the fore limbs. 

 5.9. All respiratory movements ceased, and reflexes absent. 



P. 31. — The chest was opened at once, and slight heart-movements fo\uid to be still 

 present. The bladder, notwithstanding the large quantities of urine ejected during the 

 experiment, was full. The cerebral hemispheres were found to be entirely removed ; 

 the corpora quadrigemina were intact ; the cord was found to be divided within the dura 

 mater at the level of the 5th dorsal vertebra ; the cord was crushed through rather than 

 cut through (scissors, not too sharp, having been used to divide it), but its continuity 

 was completely destroyed. 



Exp. 153. 



P.jl, Cat. Weight, 2-4 kilograms. 



2. .50. Chloroform anaesthesia induced, and spinal cord exjwsed, and completely divided 



in the mid-dorsal region ; 1 c.c. of a 5-per-cent. solution of tutin was then 



injected into the peritoneum, and chloroform discontinued. 

 3.0. No response to electric stimulus applied to left hind foot, but marked response 



when applied to left fore foot. 

 3.5. Slight twitching of ears and jerking of head. 

 3.14., Distinct tutin twitches of head and fore limbs, 

 3.16, Convulsion of fore part of body, accompanied by movement of tail ; hairs of tail 



have not become erect ; great salivation. 

 3.20, Convulsive movement of fore part of body continues ; a movement of the tail 



near the tip ; 1 c.c, of a 0-5-per-cent. tutin injected into peritoneum, 

 3.22. Swishing-movement of tail from side to side ; reflex response to pricking left hind 



leg with a knife distinctly obtained during conATilsion of fore part. 

 3. 28. Movement of tail during convulsion of fore part, 

 .3.29. Severe convulsions of fore part, accompanied by marked lashing -movement of 



tail. 



