364 Transactions. 



P.M. 



6.25. Recovered consciousness ; mai-ked twitching of head and ears ; sitting up. 

 7-15. Sitting erect on fore paws ; sahvating freely ; convulsive movements of jaws. 

 7.25 Seizures almost continuous ; placed on a table ; it raises itself by straightening 

 to its fore paws, and pushes its body further and further back, then sinks forward 

 7.45. apparently exhausted, so that the fore limbs are spread out at right angles to 



the trunk ; meanwhile jaws are grinding together, and saliva seems to be 



swallowed ; pujjils moderately dilated, but as daylight nearly gone tliis may 



be natural. 

 7.57. As condition continues, gave another rectal dose of 0-6 gram chloral. After 



getting this it showed the symptoms described by Marshall, of pushing itself 



back till it actually fell backwards over its tail. The puj^il was dilated, and 



would not contract when a match was held close to it. 

 8.7. No cessation of symptoms ; fell over tail again ; interval between seizures varies,. 



about one minute ; no general con\'ulsion, as is the case when chloral is not 



given. 

 8.15. Has been quieter the last few minutes, as if dozing as it sits. 

 8.30. Lying on side, apparently under chloral ; breathing very shallow ; no twitching. 

 8.40. Respirations extremely feeble. 

 8.45. Spontaneous movements ; tried to rise ; raised head, and fell over on the other 



side. 

 9.0. No further tutin symj^toms ; moves occasionally, especially if touched. 

 9.30. Still the same ; has passed urine ; is sitting with nose in a corner of cage, as if 



dozing ; eyes half-shut ; does not mind being touched or handled ; ears cool. 

 10.0. Same, but has changed its position several times. 

 10.40. Moving about more freely ; seems to suifer from ii'ritation of the anus ; is more 



like normal than it has been since 7 p.m. 

 10.50. Same ; has jjassed some pellets of fseces and some thin fascal matter ; behave? 



normally when approached, and seems wide awake ; can use all its limbs. 

 Feb. 12. At 5 p.m. seems normal, except that it is suffering from diarrhosa. 

 ., 13. Found dead in the morning. 



Exp. 174. 

 P.m. Rabbit. Weight, 1-455 kilograms. 



5.45. Gave, per rectum, 0-6 gram chloral -hydrate. 

 5.55. Gave 13-8 minims of a 0-5-per-cent. solution tutin (3 mlgm. per kilo), hyi^o- 



dermically. 

 6.10. Animal apparently fully ansesthetised ; wTapped in a soft towel to maintain 



temperature. 

 0.25. Same. 



7.5. Dazed and sleepy looking ; no movements other than respiratory ; eyes open. 

 7.35. Made starting-movements with head, and moved hind limbs ; is still uTapped 



in towel ; removed towel. 

 8.0. Has had frequent startings, but is very quiet most of the time. 

 8.25. Sitting up, apparently dozing ; has been somewhat restless, but no sign of con- 

 vulsion ; covered it up with towel, and noticed that it has passed urine. 

 8.55. Sitting in a corner of cage, quite awake, but does not seem at ease ; still frequent 



startings ; breathing slow and deliberate. 

 0.7. Seems to feel some irritation at anus, possibly from the rectal injection ; put its 



head down, as if to lick anxis. 

 9.20. Apparently normal. 



lO.O. Has been continuously observed, but no sign of convulsions. 

 11.0. Apparently quite normal ; resists having its ears pulled ; has passed some 



fseces. 

 11.30. No further change ; sitting with eyes wide open ; easily startled. 

 Next day. Apparently normal. 



Exp. 175. 

 P.ji. Rabbit. Weight, 1-534 kilograms. 



3.15. Gave 1 c.c. (1 gram) of a solution of chloral-hydrate, per rectum, and 20-8 minims 



of a 0-5-per-cent. solution tutin, hypodermically (4 mlgm. per kilo). 

 3.25. Lying on side, under chloral anaesthesia ; respiration, 42 ]}ev minute. 

 3.45. Still sleepy imder chloral ; breathing the same ; no tutin symptoms. 

 3.49. Turned over on to tJie other side ; respirations, 40 per minute ; blinks eyes once 



or twice in succession occasionally. 

 5.0. Twitching and convulsive movements. 

 5.15. Same convulsive movements. 

 6.30. Same, but more feeble. 

 9.20. Died. 



