Table 27 Summary of results of mean counts of micronucleated erythrocytes (per 1000) in blood 

 of Platichthys stellatus collected during two seasons (November-December 1986 and January- 

 February 1987) and collected only in November-December 1986 (means ± standard deviation). 



Table 28. Percent of P. stellatus with pleomorphic nuclei (NP). Each fish was rated: 1 if 

 <5% of erythrocytes were pleomorphic; 2 if 5-50% of erythrocytes were pleomorphic; or 3 

 if >50% of erythrocytes were pleomorphic. N= sample size. 



Percent with NP rating 

 STATION 1 2 3 



Berkeley 



Oakland 



San Pablo Bay 



Vallejo 



Santa Cruz 



Russian River 



Liver Cytochrome P-450 Activity. Data were produced for a variety of end-points involving 

 the cytochrome P-450 system. Values for many of the end-points were recorded for selected 

 fish from one site (BK) injected with B-naphthoflavone (BNF), a known P-450 inducer, and 

 untreated fish from each of the five collection sites. Total cytochrome P-450 content in 

 nanomoles (nmol) per mg microsomal protein represents the native, active enzyme activity. 

 Mean total P-450 content was about three fold higher in treated fish than in equivalent 

 untreated samples (Table 29). Among the five collection sites, the highest mean values were 

 found in fish at the OK site and the lowest were at the SP and RR sites. The differences in 

 site means were less than twofold. 



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