PRINCIPAL INVESTIGATOR (S ): Arnauld E. Nicogossian, Charles F. Sawin, and 



Peter J. Bartelloni 



EXPERIMENT TITLE/NUMBER : Results of Pulmonary Function Tests 



PROGRAM/MISSION : Apollo-Soyuz Test Project 



CLASSIFICATION : Human 



DISCIPLINE(S) : Respiratory 



OBJECTIVES : To measure pulmonary function in weightlessness. 



PROTOCOL : Preflight pulmonary function tests were performed in conjunction 

 with other medical evaluations on days F-45, F-30, and F-15. Because of 

 hardware malfunction on day F-45, data were not amenable to analysis and only 

 two sets of data were used for baseline purposes. Following exposure to 

 nitrogen tetroxide and 10 minutes prebreathing of 100% oxygen, pulmonary 

 function screening tests were obtained on all three crewmembers on recovery 

 day aboard the prime recovery vessel. 



EQUIPMENT : Pulmonary function test equipment. 



RESULTS : Postflight pulmonary function assessment was complicated by nitrogen 

 tetroxide inhalation during recovery. Discomfort associated with deep 

 inspiration and breath holding was noted R+1 and R+2. Parameters measured 

 were: capacities (total lung, residual, vital, forced vital), flow rates 

 (maximum expiratory, maximum midexpiratory, expiratory in 1 S), closing 

 volume, closing capacity, single breath cabron monoxide diffusing capacity. 

 Decreased diffusing capacity occurred until R+13 (50% in one crewman). 



CONCLUSIONS : No significant postflight changes were observed when compared to 

 the preflight means. The R+29 data obtained from the three crewmembers showed 

 that the measured pulmonary function parameters, including DLC0„ B and repeat 

 blood gas determinations (breathing room air and 100% oxygen), were within 

 normal limits. 



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