Feb., 1906.] The Cause of Trembles in Cattle. 469 



viscera, including some liver, and might have eaten much more, 

 if permitted. At 9 A. M. still trembled, but not so much; at 

 10:45 could see no trembling; at 4 P. M. very little trembling 

 when held up until after exercise when it was plain. Dec. 17, 

 temperature at 9:10 A. M.. 103°, at 3:30 P. M., 103.2°. Tremb- 

 ling; at 9:10, none; at 10 o'clock, after considerable exercise, 

 hind legs trembled and after drinking milk (she would take none 

 with snake-root in it) , the hind legs and right front leg trembled 

 strongly when she was held up; at 3:30 trembling mostly in left 

 hind leg and that not till she had been held some seconds. She 

 continued active and appetite good. Killed Dec. 17, but not 

 examined until Dec. 26, w^hen the only abnormal appearance 

 was a general venous engorgement (likely due to the CS,, which 

 killed her?). The experiments with this cat proved that trem- 

 bles could be produced by thoroughly boiled extract of snake- 

 root. The later experiments showed that she would no longer 

 take milk containing the poison but would take meat greedily, 

 also that this meat brought on the trembling again, but her 

 first experience appeared to have effected some degree of toler- 

 ance of the poison, for she was not so strongly affected as a 

 larger cat which ate a smaller quantity of meat from the same 

 rabbit. This was 



No. 3. A female cat, weight about 3^4 pounds; was fed 

 like No. 2 with meat from rabbit, No. 6. A hind leg was given 

 at 8 A. M., Dec. 14, but at 3:40 P. M. had not been eaten. At 

 7:50 the next morning she had taken this and some good milk. 

 A fore leg and side were put in, but had not been eaten at 10 

 o'clock. At 4:10 P. M. the larger part had been eaten. No 

 trembling that day. At 5:50 P. M. left her half of liver. 



Of this piece about one-third remained the next morning and 

 was given to No. 2, which had eaten other half of liver. After 

 being out of box a few minutes she returned voluntarilv. Then, 

 for the first time I could feel trembling and on holding her up 

 could see strong trembling of hind legs. 9 A. M., trembled 

 some; at 10:45 did not tremble, had not eaten much of the meat 

 left earlier, drank good cold milk and a few minutes later, when 

 I held her up she trembled so that I could feel it and see it in her 

 legs, three or four of them; 4 P. M., trembled some and, after a 

 very little exercise, strongly. On putting her on window sill, 

 3rd floor, and letting her look out, trembling was quite notice- 

 able even without holding up. After being let free on the floor 

 a little while trembling was very strong; apparently indisposed 

 to exercise. When returned to box began eating rabbit. 



Dec. 17, 8:50 A. M., rabbit meat consumed except large 

 intestine containing snake-root She seemed no worse ; respira- 

 tions 40 and 36 per minute, doubtless increased by fear; temper- 

 ature at 9:45 A. M., lOl:'?^"; trembling that day no greater than 



