102 



HOLLAENDER, StAPLETON AND BuRNETT 



Doermann (personal communication) in our laboratory 

 found that there is a linear relation between concentration 

 of glycerol and its protective capacity. More complete 

 investigation of the glycols as well as more simple alcohols 



1000- 



PROTECriVE ACTION OF SH COMPOUNDS 



8AL 



CYSTEINE 



X-RAY DOSE • 60 KILOROENTGENS 



A.2'C 

 BROTH-GROWN CELLS 



o.odial 0005 



0.0026 



O.Ol 0.02 



MOLAR CONCENTRATION 



004 



Fig. 4. Survival of E. coli in buffer suspension of different 



concentrations of BAL and cysteine. Burnett, Stapleton, 



Morse and Hollaender (1951). 



has revealed that all of them have essentially similar charac- 

 teristics both in regard to the concentrations required to give 

 detectable protection as well as the degree of protection 

 afforded by optimum concentrations. Concentrations required 

 to give protection are of the order of a hundred times that 

 required for the sulphydryl compounds, as shown in Fig. 5. 



