Synthesis of Nucleosides and Nucleotides 171 



for studies on individual tissues and also the possible pitfalls 

 to be encountered in comparing results obtained with different 

 precursors. 



REFERENCES 



Balis, M. E., Brown, G. B., Elion, G. B., Hitchings, G. H., and 



Vanderwerff, H. (1951). J. biol. Chem., 188, 217. 

 Balis, M. E., Marrian, D. H., and Brown, G. B. (1951). J. Amer. 



chem. Soc, in press. 

 Bendich, a., and Brown, G. B. (1948). J. biol. Chem., 176, 1471. 

 Bergstrand, a., Eliasson, N. A., Hammarsten, E., Norberg, B., 



Reichard, p., and von Ubisch, H. (1948). Cold. Spr. Harb. Sym. 



quant. Biol., 13, 22. 

 Brown, G. B. (1948). Cold Spr. Harb. Sym. quant. Biol., 13, 43. 

 Brown, G. B., Bendich, A., Roll, P. M., Sugiura, K. (1949). Proc. 



Soc. exp. Biol., N.Y., 72, 501. 

 Brown, G. B., Roll, P. M., Plentl, A. A., and Cavalieri, L. F. (1948). 



J. biol. Chem., 172, 469. 

 Carter, C. E., and Cohn, W. E. (1949). Fed. Proc, 8, 190. 

 Cohn, W. E. (1950). J. Amer. chem. Soc, 72, 1471. 

 Davoll, J., Lythgoe, B., and Todd, A. R. (1948). J. chem. Soc, 967 



and 1685. 

 Davoll, J., and Lowy, B. A. (1951). J. Amer. chem. Soc, in press. 

 Elwyn, D., and Sprinson, D. B. (1950). J. Amer. chem. Soc, 72, 3317. 

 FuRST, S. S., Roll, P. M., and Brown, G. B. (1950). J. biol. Chem., 



183, 251. 

 Hammarsten, E., Reichard, P., and Saluste, E. (1949). Acta chem. 



Scand., 3, 433. 

 Hammarsten, E., and Reichard, P. (1950). Acta chem. Scand., 4, 



711. 

 Hammarsten, E., Reichard, P., and Saluste, E. (1950). J. biol. 



Chem., 183, 105. 

 Kerr, S. E., Seraidarian, K., and Brown, G. B. (1951). J. biol. 



Chem., 188, 207. 

 LePage, G. a., and Heidelberger, C. (1951). J. biol. Chem.. 188, 593. 

 Marrian, D. H., Spicer, V. E., Balis, M. E., and Brown, G. B. (1951). 



J. biol. Chem., 189, 533. 

 Plentl, A., and Schoenheimer, R. (1944). J. biol. Chem., 153, 203. 

 Reichard, P., and Estborn, B. (19^51). J. biol. Chem., 188, 839. 

 Roll, P. M., Brown, G. B., DiCarlo, F., and Schultz, A. A. (1949). 



J. biol. Chem., 180, 333. 

 Roll, P. M., and Weliky, I. (1951). Fed. Proc, in press. 

 Totter, J. R., Volkin. E., and Carter, C. E. (1950). Abstracts, 118th 



Meeting, Amer. Chem. Soc, 55c. 



DISCUSSION 



Heidelberger: While we are on the subject of these different 

 precursors of purines I would like to mention some of our experiments. 



