Rate of Protein Synthesis in Man 



199 



The data from a typical experiment are given in Table II. 

 With these data we determine the time at which the urea 



Table II 

 Rate of Utilization of Glycine Nitrogen by Human Subject (DR-1) 



*Eu = 8-95g. N/day 

 U=5-65g. N 



fCorrection: 



B = 83-2/day Et = 11 - 5 g. N/day 

 P = 0-612g. N. Ao=44-8mg. »N 



17-24-9 

 213 



— 3-70 per cent/day. 



concentration attains its maximum value. At this time 



Eu 

 U 



E 



u 



U*^max.__-g g-Bt 



''max. 



(10) 



B is calculated from this equation and used in equation (8) 

 to calculate P. S is determined by equation (11). 



S=BP-Et 



(11) 



There is certain evidence that these calculations approxi- 

 mate the real situation. From equation 7 we deduce that 

 the administered amino-acid is rapidly cleared from the 

 metabolic pool. The rapid decrease in the ^^N concentration 

 of the urinary ammonia is consistent with this, for the urinary 



