286 



Index 



Deoxyribonucleic acid. See also 

 Nucleic acids, 

 extraction from tissue, 173-188 

 incorporation of c>i:idine and 

 cytidylic acid, 168-170 

 of glycine, 171-174 

 purine nucleotides and, 168-170 

 pvrimidine nucleotides, biosyn- 



* thesis of, 152-163 

 synthesis, and mitotic cycle, 

 138-151 

 as shown by autoradiographs, 



123-124, 127, 138-151 

 effect of X-rays on, 114-120 

 effect of shock on, 119 

 in liver, 149-151 

 two forms of, 149-150, 173, 174 

 virus, 161-162 

 Deuterium, 14-16, 26, 28-40, 196 

 Diabetes, 22-23, 279-283 

 2:6-Dianiinopurine, 211-212 

 j8-Dimethylacrylate, 24, 26 



Enzymes, and asymmetric citric 

 acid, 246-257 

 and X-ray damage, 119-120 

 Escherichia coli, and pyrimidine bio- 

 synthesis, 160-161 

 protection against X-rays, 97-1 1 1 

 Ethanol, 26, 103, 104, 106-108 



Fasting, 281-282 



Fatty acids, biosynthesis of, 258-283 

 in cholesterol biosynthesis, 18 

 insulin effect, 277-283 

 X-rays and, 104-105, 106, 108 

 Fibroblasts, autoradiographs, 123- 



124 

 Folic acid antagonists, 121 

 Formate and formaldehyde, and 

 acetone metabolism, 232-238, 

 242-243 

 and cholesterol biosynthesis, 21 

 and porphyrin biosynthesis, 67 

 and X-rays, 106 

 in propionic acid fermentation, 



238-243, 245 

 incorporation into RNA, 170 



Gamma- radiation, 120 



Globin, 74-83 



Glucose, and haem synthesis, 87 

 and radiation, 110-111 

 cyclization of, 220-221, 224-225 

 indicator of carbohydrate meta- 

 bolism, 227-245 



Glucose — continued 



precursor of amino-acids, 213-223 

 precursor of milk fat, 269-276 

 Glycerol, in fat synthesis, 274, 277- 

 278, 283 

 propionic acid fermentation, 238- 

 245 

 Glycine, biosvnthesis of in yeast, 

 218, 223 

 in biosynthesis of nucleic acids, 

 149-150, 171-174, 203-211 

 of porphyrins, 43-51, 63, 86-89 

 of proteins, 74-83, 197-211 

 life-span of red blood cells, 69-82 

 Glycogen, 227-245 

 Glycols, 102, 110 

 Granules. See Particles, cellular. 

 Growth hormone, 23, 281, 283 

 Guanine, 168-169, 211-212 

 Guanosine, 166-167 

 Guanylic acid, 166-169, 181-182 



Haemoglobin, 41-95 



haem biosynthesis, energy sources 

 for, 86-89 

 porphyrins, 41-67 

 iron as tracer for, 93 

 life-span of red blood cell, 68-82 

 time sequence for haem and globin, 

 82-83 

 Haemolysis, 86-87, 89 

 Hen, anaemic, haemoglobin formation 

 in, 82-83 

 protein and nucleic acid turnover 

 in, 205-206 

 Hexoestrol, tritiated, 12 

 Histones, effect of X-rays on, 117, 



118 

 Houssay animals, 22, 281, 283 

 Hyperthyroidism, 91-93 

 Hypoxaemia, 91-93, 95 



Infection, uptake of iron in, 92-94 

 Insulin, 277-283 



Iodine (^^^I), autoradiographs, 133- 

 136 

 labelled iodo-cestradiol, 6, 10 

 labelled thvroxine, 12 

 Ion exchange, 154-157, 163, 166, 



173, 214 

 lonophoresis, 180-183 

 Iron (^^Fe, ^^Fe), criterion of radia- 

 tion damage, 112 

 uptake in disease, 90-95, 112- 

 113 

 Isoprene unit, 24 



