Index 



287 



Isovalerate, in cholesterol biosyn- 

 thesis, 20 



Jensen rat sarcoma, 114-121 



See Citric acid 



a-Ketoglutarate. 



cycle. 



Kojic Acid, 224-225 



Lactate, in acetone metabolism, 



232-235, 245 

 Lactobacillus bulgaricus, 160 

 Lactobacillus casei, 211-212 

 Lead salts, and haem synthesis, 88-89 

 Lipoidosis, 14-16 



Liver, cholesterol synthesis in vitro, 

 17-24 



fatty acid synthesis in vitro, 278- 

 283 



glycogen, 227-245 



mitosis rate in, 149-151 



nucleic acid synthesis in, 148-151, 

 171-172, 205-210 



protein synthesis in, 205-210 



pyrimidine nucleotide synthesis in 

 vitro, 156-159 



regenerating, vacuolation in, 163 



uptake of iron in disease, 91-94, 113 

 Lysine, biosynthesis in yeast, 215- 



216 



Mammary gland, milk fat in, 258- 

 278 



Metabolic pool, 190-202 



Methanol, 103, 244-245 



Methyl glyoxal, 245 



Mice, protection against X-rays, 111 



Microsomes. See Particles, cellular. 



Mitosis, 120-121 



and nucleic acid synthesis, 138-151 

 and protein synthesis, 209 

 effect of radioactive tracers on, 137 

 of shock on, 117, 119 

 of X-rays on, 115-116, 147 



Neutrons, radiation damage, 109- 



110 

 Nitrogen (^^N) in haemoglobin meta- 

 bolism, 44-45, 50, 69-72, 82-89 

 in nucleic acid metabolism, 121, 



164-171, 174 

 in protein metabolism, 82-83, 

 190-211 

 Nuclei, components of, 181-183, 206- 

 209 



Nucleic acids, 152-189. See also 

 Deoxyribonucleic acid, Nu- 

 cleoproteins. Nucleosides, 



Nucleotides, Ribonucleic acid, 

 and names of individual 

 purines and pyrimidines. 

 extraction of, 175-183 

 synthesis, and protein synthesis, 

 206-212 

 effect of Amethopterin on, 121 

 effect of X-rays on, 114-121 

 Nucleoproteins, 144-145, 184-189 

 Nucleosides, purine, synthesis of, 



165-167 

 Nucleotides, incorporation into 

 RNA, 168-169 

 ionophoresis separation of, 180-183 

 purine, biosynthesis of, 165-166 

 pyrimidine, biosynthesis of, 152- 

 163 



CEstrogens, carbon-labelled, 4-13 



deuterium-labelled, 30-31, 38 



iodine-labelled, 6, 10 



tritium-labelled, 12 

 Orotic acid, 152-163 

 Oxaloacetic acid. See Citric acid 



cycle 

 Oxygen, and X-ray sensitivity, 96- 



99, 104, 108 



Paramecium, and X-rays, 111 

 Particles, cellular, autocatalytic 

 duplication of, 184-189 

 phospholipid turnover in, 189 

 ribonucleotide components, 181-183 

 Pentose nucleic acid. See Ribo- 

 nucleic acid. 

 Phenylalanine, biosynthesis in 



yeast, 213-226 

 Phosphate, in iron metabolism, 



94-95 

 Phosphatides, 211 

 "Phosphoprotein," 175-181 

 Phosphorus (^^P), autoradiographs, 

 123-124, 127, 133-135, 137- 

 151 

 nucleic acid experiments, 115- 

 121, 123-124, 127, 137-151, 

 175-189 

 Phosphorylation, inhibition of, 88- 



89, 119-120 

 Pituitary, 12 

 Polytomella coeca, 184-189 

 Porphyrins. See also Haemoglobin, 

 mechanism of biosynthesis, 41-67 



