140 A. D. LEES 



pupa) is wounded or subjected to surgical operations. The 

 effect is not localised but is due to increased oxygen consump- 

 tion throughout the body. The stimulated respiration is certainly 

 associated with the synthesis of cytochrome c, since the stimu- 

 lated respiration is inhibited by CO. Nevertheless, it is significant 

 that although the metabolism may be raised almost to the level 

 found in the developing insect, no development in fact takes 

 place, since there is no secretion from the prothoracic glands. 

 The endocrine system is therefore the prime mover in the 

 control of diapause. 



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