IN VIVO l-L'NCTION Ol- SlliCILULAK PAKTlCLlvS 



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Fic. I. Phase-contrast photomicrograph of transphintablc liver tumor cells in a polyvinyl- 

 pyrollidone-sucrose homogenate. | From (29).) The cells, somewhat flattened, show large clear 

 nuclei, small elongate mitochondria, and spherical lipid droplets. Objects in focus appear dark 

 or gray, those out of focus arc bright. X 950- 



Fig. 2. Phase-contrast plmtomicrograph of parcnch\ matDiis cells of rat lixcr in a polyvinvl- 

 pyroUidone-sucrose homogenate. [From (29).] The cytoplasm cuntains many large elongate 

 mitochondria. X 925. 



FiG. },. Electron micrograph of section of mitochondrial fraction. This is an unwashed frac- 

 tion obtained from a 0.88 m sucrose homogenate of rat liver. The mitochondria are well 

 preserved: their cristae apjiear as lighter areas. Microsomal contamination is shown bv arrows. 



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