INDEX 



21 I 



homogeneity and individuality of, 131-140 



membrane, 129 



morphological identification of, 140-14;} 



rupture, 155 

 Lysosomc-like particles, 143-145 



from beef thyroid and brain, 144 



from kidney, 143 



from lower organisms, 145 



from spleen, 144 

 Lysosome-rich fractions 



ferritin content, 143-144 



other bodies in, 143 



JVLatrix systems, 44-58 



cellulose, 44—46 



chitm, 44-46 



Dowex, 50 



methylcellulose, 45-46 



mineral and mineral gel, 47 



pectic acid, 47 

 Melanin formation, 50-54 



criteria, 51 



effect of protein matrix, 51-53 



from paraquinone, 51 



without matrix, 51 

 Mclanins, 50-51, 54 



relation of synthetic polyquinones to, 54-56 

 Microbodies, 140 



Microsomal amino acid incorporation, 160- 

 162 



ATP dependence, 162 



factor requirements, 162 



GTP dependence, 162 



pH 5 fraction, 162 



relation to protein synthesis, 162 

 Microsomal RNA, 160 

 Microvilli, 5, 7 

 Mitochondria, 8, 65-70, 84-101 



association with lipid inclusions, 66-70 



beef-heart, 84-85 



fatty acid oxidation in, 70 



inner membrane of, 70 



isolated suspensions, 8, 84-86 

 Mitochondrial degradation, 85-86 



electron transport particle, 87 



frozen-thawed, sonicated, 86 



intact, 85-86 

 Mitochondrial organization, 88-89 

 M. lysodeilitictis, pH constancy in, 31 



A'/, vernicaria, 29 

 Mycobacterium phhi, kh 



Nucleolar RNA, 8, 176-184 



rate of synthesis, 179-183 

 Nucleotide incorporation by S-RNA 



CTP requirement, 164 



pyrophosphate iiihibitiDn. \h^ 



Urganelle jireservation, 4-5 

 Osmium fixation, limitations of, 4 

 Oxidative enzyme activity of cells, 14, 16-17 



DPNH -cytochrome c retluctase, 16, 17 



staining method, 14, 17 

 Oxidative phosphorylation, 9, 85, 91 



site, in mitochondria, 9 



JTcribiliary bodies, 5, 140 

 Peroxidase, induction of, 43 

 Phosphatase activity of cells, 12-14 



acid phosphatase, 14 



ATPase, 12, 13 



by electron microscopy, 12, 13 



in KupfTer cells, 14 



in peribiliary bodies, 14, 15 



localization, 12-14 



5'-nucleotidase, 12 



staining methods, 12 

 pH optimum of conjugated vs. dissociated 



malic oxidase, 31 

 pH shift, theory, 24-26 



chemical potential, 26 



IJonnan equilibrium, 24 



effective dissociation constant, 25 



electrokinetic potential, 25 

 pH shift, values, 27, 28 

 Photophosphorylation, 1 04-1 1 2 



DPNH reciuircmcnt, 108 



effect of phcnazine mcthosulfate, 108 



formation of ATP, iio-iii 



general reaction, 105-107 



history, 105-107 



interactions with inhibitors, 108-109 



relation to electron transport, 105, iio— iii 



requirements of, 108 



role of vitamin K, 111-112 



significance of, 1 09-1 12 



succinate requirement, 108 



TPN requirement, 108 

 Photosynthetic jiarticles, 104-105 



chlorojilasts, 104 



