CONTENTS 



Chemical Structure as a Guide to the Study of Biochemical Syn- 

 theses 

 by Konrad Block 474 



The Role of Nucleotides and Coenzymes in Enzymatic Processes 



by Frank M. Huennekens 493 



The Biosynthesis of Porphyrins; The Succinate-Glycine Cycle 



by David Shemin 518 



Problems in the Study of Multiple Enzyme Systems 



by G. Robert Greenberg 537 



Enzyme Kinetics 



by Robert A. Alberty 560 



The Interconversion of Sugars in Nature 



by Luis F. Leloir 585 



A Theory of the Primary Event in Muscle Action 



by Manuel F. Morales and Jean Bolts 609 



Trends in the Biochemistry of Nerve Activity 



by David Nachmansohn and Irwin B. Wilson 628 



Blood : Some Functional Considerations 



by Douglas M. Surgenor 653 



An Integrated Concept of Carcinogenesis 



by Harold P. Rusch 675 



XVI 



