A. D. HERSHEY 



acids, and proteins, during the synthesis of at least two of these 

 classes of substance. But to state them in this way is to ignore 

 the unique problems presented by T2. These depend on the 

 fact that the material thread connecting parental and offspring 

 virus seems to be an analytically recognizable deoxyribonucleic 

 acid and nothing else. The real biochemical problems for the 

 present are the relation of this substance to viral inheritance, on 

 the one hand, and the degree of autonomy of nucleic acid repli- 

 cation, on the other. No outstanding solution to these problems 

 has come from the work with T2. Yet many experiments that 

 might have yielded very depressing results have failed to do so. 

 On the contrary, their net effect is to increase the hope one 

 attaches to the many penetrating experiments that remain to 

 be done. 



References 



1. Anderson, T. F., Botan. Rev., 15, 464 (1949). 



2. Anderson, T. F., Cold Spring Harbor Symposia Quant. Biol., 18, 197 (1953). 



3. Beadle, G. W., in D. E. Green, ed.. Currents in Biochemical Research. 

 Interscience, New York-London, 1946. 



4. Benzer, S., personal communication. 



5. Bertani, G., Cold Spring Harbor Symposia Quant. Biol., 18, 65 (1953). 



6. Cohen, S. S., Cold Spring Harbor Symposia Quant. Biol., 12, 35 (1947). 



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11. Doermann, A. H., Cold Spring Harbor Symposia Quant. Biol., 18, 3 (1953). 



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17. French, R. C, J. Bacterial., 67, 45 (1954). 



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