BRITTON CHANCE 



In the computer that we have been using the concentrations are 

 represented by voltages, and mathematical operations upon 



!>jM{a '"a"',c"; DPN) 40;jM Op 



Time (sec) 



I;jM{ 



. >" III III , 



a^,a ,c ,DPN) 40uM 0, 

 I L 



/f 



' 0.5 B ,^ 



Tim« (sec)/ 



Fig. 5. An analogue computer representation of the kinetics of 

 oxidation and reduction of members of the abbreviated respiratory se- 

 quences : 



Oi > Oi > a )■ c > DPN > substrate 



caused by adding oxygen to the anaerobic components. 



The top trace (A) is on a slow time scale and shows the complete 

 "cycles" of the four components and the oxygen kinetics as well. The lower 

 trace (B) is on an expanded scale and shows clearly that the time sequence of 

 oxidation of the components is the sequence in which they react in the respira- 

 tory chain (AC-64). 



326 



