Frederick M. Allen 9 



4. The production of chronic hypertension by intermittent clamping of the 

 pedicles of explanted kidneys, described by Loesch prior to Goldblatt's work, 

 is confirmed. 



5. One of the features of superiority in the Loesch iiic iliod is its suiiability 

 not only for the above-described j^lnsiological observations Inii also loi studies 

 of renal pathology, which are now in progress. 



Fig. 3. Example of lesions in dogs with chronic hypertension, produced by 

 intermittent clamping of kidney pedicles (Loesch). 



REFERENCES 



1. Allen, F. M.: Studies concerning Glycosuria and Diabetes (Cambridge, Mass.: 1913). 



2. Allen, F. M.: Jl. Metabol. Resrch. 1:221. 1922. 



3. Loesch, }.; Witts, L. J., and Zimmermann, A.: Jl. Metabol. Resrcli. (i:2()7, 1924. 



4. Loesch. J., and Witts, L. ].: Jl. Metabol. Resrch. 6:339. 1924- 



5. Barcroft, J., and Stephens, J. G.: Jl. Physiol. 64: 1, 1927-28. 



6. Allen, F. NL: Jl. Metabol. Resrch. 7/8:217, 1925-26. 



7. Loesch, J.: Archs. Pathol. 4:495, 1927- 



8. Loesch, J.: Zntrlblt. f. inner. Med. 54:145. '77- '9-53- 



9. Rhoads, C. P.: Science (n.s.) 73:417' '93'- 



10. Rhoads, C. P.: Amer. Jl. Physiol. 109:324, 1934. 



