586 Hermaphroditism in the Monkey 



day of pregnancy and the fetus was found to have degenerated to a fibrous 

 mass. Since pregnancy during the previous year had terminated with the birth 

 of a normal baby, this deleterious result may have been the effect of the ad- 

 ministered hormone. 



Monkey 77, which had not been pregnant previously, received 220 mg. of 

 testosterone propionate between the sixtieth and the one hundredth day, a 

 quantity less than that tolerated by monkeys 96 and 59. On the one hundredth 

 day, the uterus was opened and found to contain a macerated fetus and 



placenta. 



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Sinus hairs were present on the supraorbital areas and also circumorally in 

 the fetuses of both treated and untreated animals. The remainder of the hairy 

 coat, except that on the head, had not appeared in any fetus. Teeth do not 

 appear until after term birth. 



Fetus 86, Untreated Control Male. The external genitalia were well formed. 

 The anterior border of the scrotum, lying 2.6 cm. ventrocephalad to the ischial 

 callosities, appeared as a turgid, partially bilobed swelling with a prominent 

 median raphe, which was especially marked on the cephalic border of the 

 scrotum from whence it extended to the under surface of the penis. The 

 meatus was present as a sagittally placed slit. The prepuce was not distinct 

 from the glans. The external appearance of this animal was similar to fetus 68 

 as shown in plate 1, figure 2. 



Sections of the testis with epididymis and selected regions of the reproduc- 

 tive tract are shown in plate 2, figures 7 to 10, for comparison with androgen- 

 treated male and female fetuses. 



The freely branching seminal vesicles were compressed to bluntly pyramidal 

 structures. The lumen of each branch was circular in cross section, lined with 

 cuboidal epithelium and occupied about one-third of the diameter. The lumen 

 was somewhat narrow toward the ends of the branches and enlarged as it 

 parsed backward to the stalk of the gland. The stalk lay in the connective-tissue 

 mass with the vas deferens of the same side. 



Tissue of the cephalic lobe of the prostate was present dorsal to the ejacula- 

 tory ducts and also ventrally between ducts and the urethra. This lobe of the 

 prostate was loosely arranged, and isolated blunt ends of rudimentary glands 

 protruded into the mass of connective tissue. The fibromuscular stroma of the 

 cephalic lobe contained solid epithelial cores in which an occasional lumen 

 had formed. Plate 2, figure 8, shows this part of the prostate. The utriculus 

 masculinus can be seen between the relatively larger ejaculatory ducts. 



The caudal lobe of the prostate was the more compact and was situated on 

 the dorsal wall of the urethra and for the most part below the entrance of the 

 ejaculatory ducts into the urethra (pi. 2, fig. 9). The caudal lobe consisted 

 chiefly of solid branching cords of epithelial cells with no lumen except in the 

 ducts of the gland near their entrance to the urethra. 



