588 Hermaphroditism in the Monkey 



fibrous connective tissue in a position analogous to the structure forming the 

 OS penis. The prepuce remained attached to the glans, both circumferentially 

 and as a deep sagittal penetration on the under surface of the clitoris. 



There was no modification of the skin and underlying tissue in the region 

 over the pubic bones. 



Fetus 68, Treated Genetic Male. The mother of this fetus received daily 

 injections of 10 mg. of testosterone propionate from the fifty-eighth to the one 

 hundred eighth day of gestation, a total dosage of 270 mg. The external 

 genitalia of the fetus (pi. 1, fig. 2) are well developed, normal in appearance, 

 and not appreciably enlarged. 



Plate 4, figures 16 to 20, are of histological sections comparable to those of 

 the untreated control male, fetus 86, shown in plate 2, figures 7 to 10. The 

 two lobes of the prostate gland and the bulbo-urethral glands of the treated 

 male fetus were larger than those of the untreated male. The fibromuscular 

 structure throughout the whole genital tract appeared better developed. In 

 the injected fetus the pattern of the urethral lumen at the various levels and 

 the contour of the surrounding parts were characteristic of the infant or young 

 monkey. However, some of this increase in size and development must be dis- 

 counted when it is noted that the control male fetus (96 days and 138 mg.) was 

 younger and smaller than the injected fetus (109 days and 200 mg.). Histo- 

 logically, the bulbo-urethral glands of the injected male apparently reflected 

 androgenic stimulation. Changes in the prostate and seminal vesicles were less 

 distinct. 



In the medullary portion of the testis of fetus 68 there is a longitudinal 

 core of irregular, communicating spaces lined with a single layer of low 

 cuboidal cells (pi. 4, fig. 16). The longitudinal section in plate 4, figure 16, can 

 be compared with plate 2, figure 7, a cross section of the testis of the untreated 

 male, fetus 86. 



The epididymal tube was lined with a single layer of cuboidal cells with 

 large nuclei and comparatively little cytoplasm. The histological character 

 of the epithelium was similar to that in the epididymis of the untreated 

 fetus. 



Fetus 6^, Partially Modified Female (pi. 1, fig. 4). The treatment of the 

 mother of this animal was deferred until the sixty-ninth day of pregnancy and 

 then continued through the ninety-ninth day. Also, the amount of testosterone 

 propionate employed was relatively small, 5 mg. per day with a total dosage 

 of 152 mg. The vestibular orifice lay between the ischial callosities in the 

 normal location for the female, and was surmounted by a clitoris, also in 

 the normal position. However, the edges of the lateral walls of the vestibular 

 orifice were irregular, clearly indicating a defect in their formation. The 

 clitoris protruded for a distance of several millimeters and possessed a distinct 

 glans covered only partly by the frenulum. Bilobed "scrotal swellings" were 

 developed over the symphysis pubis. 



