SPECIFICITY OF GENE EFFECTS 



249 



as are those of the Australian crested of the equivalent reactivities of the 

 three Australian species. 



Although the reagent for the hybrid substance did not agglutinate the 

 cells of livia, it invariably clumped those of the hybrids between pigeon 

 (livia) and Ring dove. As previously reported (Irwin and Cole, 1936), these 

 hybrids also contain a hybrid substance. Because of the cross reactions exist- 

 ing between these two hybrid substances, a certain degree of similarity can 

 be assumed. That the fraction in the hybrid substance of the Fi-Pearlneck X 



DIAGRAMMATIC REPRESENTATION OF THE'HYBRID SUBSTANCE" 

 OF THE HYBRID BETWEEN PEARLNECK AND RINGDOVE 



VPEARLNECK>- 



^^■•^V-VV:- 



COMMON- >•:•.■•. '.<,"•.•••: 



RINGDOVE 



O O O O O 



O O O 



O O O ^ Q 



o O O OO 



O o 



n PEARLNECK 

 ^i RINGDOVE 



HYBRID SUBSTANCE 



dx-A 



d<-B 



dii-C 



MrBRIO SUBSTANCE ASSOCIATED 



WITH SPECIFIC PEARLNECK SUBSTANCES 



RELATED SUBSTANCES 



Fig. 15.2— The separation into constituent parts of the hybrid substance of the species 



hybrid between Pearlneck and Ring dove. 



Ring dove, which is primarily if not entirely responsible for the cross reac- 

 tions, is dx-A may be deduced from Table 15.3, in that this fraction (associ- 

 ated with d-ll) is the only one which will exhaust the antibodies from the 

 reagent for the cells of the pigeon-Ring dove hybrid (column 5). Also, in 

 unpublished tests the reagent for the hybrid substance of the pigeon-Ring 

 dove hybrid (anti-hybrid serum absorbed by the cells of pigeon and Ring 

 dove) did not react with Pearlneck cells, but reacted strongly with d-ll cells, 

 presumably by virtue of their content of the dx-A fraction, and not definitely 

 with cells carrying dx-B or dx-C. If the dx-A hybrid substance of the species 

 hybrids between Pearlneck and Ring dove were partially or largely a rear- 

 rangement of an antigenic substance, in this case d-ll, which is species spe- 

 cific to Pearlneck — since the Ring dove is a common parent of the two kinds 



