CIRCULATIOX OF PHOSPHORUS IN THE FROCi 



389 



Tablk 5. — Froo TII, Kept at 2°, Killkd aktkh 21 Days 

 Ash wciglit: 3.104 gm 



VVeiirlil of tresh tissue Weight oi asli 



Right tibia epiphysis 

 Left tibia epiphysis . 

 Right tibia diaphysis 

 Left tibia tliaphysis . 



Right euir 



Left calf 



1.269 

 1.252 



Per cent ut ImIjcHciI 



V ailministered found 



in 1 gm fresh tissue 



0.42 



(luring the formation of such crystallites from a plasma containing 

 labelled phosphate. The dissolution of "old" apatite crystals and the 

 formation of "new" ones is, however, a comparatively slow process 

 and is restricted to a fraction of the bone apatite. In contrast to the 



Table 6. — Frog IV, Kept at 2°, Killed after 22 D.ws 

 .\sh \\'eight: 3.347 gm 



W eisjt of fresli tissue 



j Per cent o£ laholled P 

 Weight of ash | administered found 

 in 1 gm fresh tissue 



Right tibia epipliysis 

 Left tibia epiphy.sis . 

 Right tibia diaphysi.s 

 Left tibia diaphysis . 



Right thigh 



Left thigh 



Right calf 



Left calf 



mgm 



144.2 



158.7 



205.8 



215.2 



4.116 

 4.109 

 1.477 

 1.548 



3.6S 

 4.50 

 5.07 

 4.52 



(t.2() 

 0.29 

 0.34 

 0.36 



bones, the greatest part of the phosphorus in the muscles is present as 

 a constituent of organic compounds, as seen in Table 1 b. The bulk 

 (about 80 per cent) of the organic P is prescnl in llie muscle of the 

 frog in the form of acid soluble phosphorus compounds and, in a 

 corresponding mann(>r, the ia1e of adivation of the muscle P depends 



